Multiple Imputation Methodology for Missing Data, Non-Random Response, and Panel Attrition

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  • David Brownstone
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Handling attrition and non-response in longitudinal data

Procedures for handling attrition and missing data values in longitudinal studies are discussed. A multiple imputation (MI) strategy is developed that can be applied to complex multilevel data. It is both general and statistically efficient and estimation software is available. An example of its use is given.

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Background and Objectives: A major challenge that affects the longitudinal studies is the problem of missing data. Missing in the data may result in the loss of part of the information which reduces the accuracy of the estimator and obtain the results will be biased and inaccurate. Therefore, it is necessary to evaluate the missing data mechanism from a longitudinal research and to consider thi...

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Multiple imputation for estimation of an occurrence rate in cohorts with attrition and discrete follow-up time points: a simulation study

BACKGROUND In longitudinal cohort studies, subjects may be lost to follow-up at any time during the study. This leads to attrition and thus to a risk of inaccurate and biased estimations. The purpose of this paper is to show how multiple imputation can take advantage of all the information collected during follow-up in order to estimate the cumulative probability P(E) of an event E, when the fi...

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Using multiple imputation to deal with missing data and attrition in longitudinal studies with repeated measures of patient-reported outcomes

OBJECTIVE Missing data is a ubiquitous problem in studies using patient-reported measures, decreasing sample sizes and causing possible bias. In longitudinal studies, special problems relate to attrition and death during follow-up. We describe a methodological approach for the use of multiple imputation (MI) to meet these challenges. METHODS In a cohort of patients treated with percutaneous c...

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An Empirical Comparison of Performance of the Unified Approach to Linearization of Variance Estimation after Imputation with Some Other Methods

Imputation is one of the most common methods to reduce item non_response effects. Imputation results in a complete data set, and then it is possible to use naϊve estimators. After using most of common imputation methods, mean and total (imputation estimators) are still unbiased. However their variances (imputation variances) are underestimated by naϊve variance estimators. Sampling mechanism an...

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تاریخ انتشار 2000